3D Group Deformation Maps of Adult C57BL/6J Mouse Brains
The above group deformation maps were obtained by nonlinearly registering all the target brain atlases to a reference brain atlas and then mapping the voxel displacement onto the same 3D reference space. Because the target brains were initially registered with the reference brain through affine transformation, the deformation map represents higher order geometrical variations other than global differences such as brain location or brain sizes.
The average local deformation maps of: (A) 10 in vitro individual mouse brains mapped to the average in vitro brain. (B) 12 in vivo individual mouse brains mapped to the average in vivo brain. (C) 10 in vitro individual mouse brains mapped to the average in vivo brain. (D), (E) and (F): The ventral views of (A), (B) and (C), respectively. (G) A cross sectional view of (B) and (E). Note: the images are not strictly proportional. The color represents the average distance a given voxel underwent following registration of each of the individual brains to the average brain template.